Dengue virus: structure, serotypes and mode of.
Dengue virus is a small virus that carries a single strand of RNA as its genome. The genome encodes only ten proteins. Three of these are structural proteins that form the coat of the virus and deliver the RNA to target cells, and seven of them are nonstructural proteins that orchestrate the production of new viruses once the virus gets inside the cell.
The Aedes aegypti mosquito is the host and vector of the Dengue virus type 2 (also called DENV-2). The mosquito gets the virus from ingesting the blood of infected humans. Dengue Fever is caused by this arbovirus virus that has a genome made up of single stranded ribonucleic acid (RNA) (Sanchez-Vargas, et.al., 2009). Using an outer-envelope protein as an anchoring tool, it attaches to the.
The virus that causes dengue is transmitted by mosquitoes. Dengue fever usually starts with a fever, joint pain, rash and nausea. Without treatment, the virus can cause damage to blood and lymph vessels and lead to dengue hemorrhagic fever, which is marked by difficulty breathing, bruising and bleeding from the nose, gums or under the skin. Each year, the virus infects up to 100 million people.
Dengue virus 1 (DEN-1) was first discovered in Japan in the 1940s. The other three viruses, DEN-2, DEN-3, and DEN-4, are closely related to DEN-1, but are not recognized as the same virus by.
It has been shown that the structure of mature ZV is arranged in a herringbone pattern with 90 antiparallel envelope dimers (9,10), similar to the structure of dengue virus (11, 12). The dengue.
INTRODUCTION The dengue virus causes dengue and dengue hemorrhagic fever. It is an arboivirus, within thia group it is from the family Flavivirade, which includes hepatitis c, West Nile, yellow fever and Japanese and St. Louis encephalitis. All these viruses are spread by mosquitoes. The two types of mosquitoes that spread dengue are Aedes aegypti and Aedes albopictus, Aedes aegypti being the.
This animation zooms into a 3D model of dengue virus, moving from the virus’s outer structures to its inner core. As shown in the animation, the outside of the dengue virus is made up of glycoproteins arranged in geometric patterns of two-, three-, and five-fold symmetry. These glycoproteins float over a lipid bilayer that covers the nucleocapsid, a protein core encasing the virus’s RNA.